STRIDE-DB

Repeat Length	AFR	AMR	EUR	EAS	SAS	Repeat
13.2	4	0	0	0	0	TTTATTTTATTTTATTTTATTTTATATTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT
18.2	0	0	0	0	0	TTTATTTTATTTTATTTTATTTTATATTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT
14.2	20	0	0	0	0	TTTATTTTATTTTATTTTATTTTATATTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT
15.2	4	0	0	0	0	TTTATTTTATTTTATTTTATTTTATATTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT
16.2	8	2	4	2	2	TTTATTTTATTTTATTTTATTTTATATTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT
17.2	0	2	2	0	0	TTTATTTTATTTTATTTTATTTTATATTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATTTTATT

Position	Disease/Trait	P-value	SNPs	Location with respect to STR	distance	Study
4:160218813	Alzheimer’s disease polygenic risk score (upper quantile vs lower quantile),	3.0E-8	rs111559755	downstream	-44867	Genome-wide association of polygenic risk extremes for Alzheimer's disease in the UK Biobank.
4:160282718	Intelligence (childhood),	6.0E-6	rs6536413	upstream	19038	Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.

Position	HGVS	dbSNP id	Phenotype List	Distance	Clinvar Significance
4:160225541	NM_001394067.2(RAPGEF2):c.591A>C (p.Pro197=)	rs139146857	not provided	-38139	Benign
4:160235886	NM_001394067.2(RAPGEF2):c.819G>C (p.Glu273Asp)	rs1764342195	Epilepsy, familial adult myoclonic, 7	-27794	Uncertain significance
4:160239570	GRCh37/hg19 4q32.1(chr4:160239570-161231483)x3	NA	not provided	-24110	Uncertain significance
4:160243489	NM_001394067.2(RAPGEF2):c.854-10T>C	rs10014951	not provided	-20191	Benign
4:160251417	NM_001394067.2(RAPGEF2):c.1303-68TG[16]	NA	Epilepsy, familial adult myoclonic, 7	-12263	Benign
4:160251417	NM_001394067.2(RAPGEF2):c.1303-68TG[17]	NA	Epilepsy, familial adult myoclonic, 7	-12263	Benign
4:160251615	NM_001394067.2(RAPGEF2):c.1432T>C (p.Leu478=)	rs533771443	not provided	-12065	Likely benign
4:160252627	NM_001394067.2(RAPGEF2):c.1512C>T (p.Asp504=)	rs369891510	not provided	-11053	Benign
4:160252814	NM_001394067.2(RAPGEF2):c.1608C>T (p.Ile536=)	rs9999415	not provided	-10866	Benign
4:160254540	GRCh37/hg19 4q32.1(chr4:160254540-160373894)x3	NA	not provided	-9140	Uncertain significance
4:160264140	NM_001394067.2(RAPGEF2):c.2928C>T (p.Asn976=)	rs17038049	not provided	460	Benign
4:160267251	GRCh37/hg19 4q32.1(chr4:160267251-160472913)x3	NA	not provided	3571	Uncertain significance
4:160267936	NM_001394067.2(RAPGEF2):c.3503-5A>G	rs17038050	not provided	4256	Benign
4:160271269	NM_001394067.2(RAPGEF2):c.3713-10del	NA	Epilepsy, familial adult myoclonic, 7	7589	Benign
4:160273844	NM_001394067.2(RAPGEF2):c.3873T>G (p.Thr1291=)	rs17038055	not provided	10164	Benign
4:160277045	NM_001394067.2(RAPGEF2):c.4692T>C (p.Pro1564=)	rs1315705346	not provided	13365	Likely benign
4:160277111	NM_001394067.2(RAPGEF2):c.4758G>A (p.Pro1586=)	rs78531515	not provided	13431	Benign
4:160277276	NM_001394067.2(RAPGEF2):c.4923C>T (p.Pro1641=)	NA	Epilepsy, familial adult myoclonic, 7	13596	Benign
4:160279258	NM_001394067.2(RAPGEF2):c.4958-8A>G	rs1732314095	Epilepsy, familial adult myoclonic, 7	15578	Uncertain significance

Position	Population	BlockLength (kb)	Distance	Location with respect to STR	No. of SNPs	SNPs in the Haploblock
4:160242492-160243143	AFR	0.652	-21188	downstream	4	rs72967756, rs79433860, rs151151048, rs7385912,
4:160244212-160244287	AFR	0.076	-19468	downstream	2	rs2017052, rs201700,
4:160244212-160244287	all_pop	0.076	-19468	downstream	2	rs2017052, rs201700,
4:160244212-160248581	AMR	4.37	-19468	downstream	6	rs2017052, rs2017009, rs35234008, rs11383811, rs6857361, rs13868112,
4:160244212-160248581	EUR	4.37	-19468	downstream	6	rs2017052, rs2017009, rs35234008, rs11383811, rs6857361, rs13868112,
4:160244212-160244287	SAS	0.076	-19468	downstream	2	rs2017052, rs201700,
4:160244287-160248581	EAS	4.295	-19393	downstream	5	rs2017009, rs35234008, rs11383811, rs6857361, rs13868112,
4:160246091-160248581	AFR	2.491	-17589	downstream	5	rs35234008, rs11383811, rs6857361, rs80092244, rs13868112,
4:160246091-160248581	all_pop	2.491	-17589	downstream	4	rs35234008, rs11383811, rs6857361, rs13868112,
4:160246091-160248581	SAS	2.491	-17589	downstream	4	rs35234008, rs11383811, rs6857361, rs13868112,
4:160249334-160250695	AMR	1.362	-14346	downstream	3	rs113283199, rs10022399, rs185286,
4:160249722-160250695	AFR	0.974	-13958	downstream	3	rs10022399, rs17038043, rs185286,
4:160249722-160250695	all_pop	0.974	-13958	downstream	2	rs10022399, rs185286,
4:160249722-160250695	EAS	0.974	-13958	downstream	2	rs10022399, rs185286,
4:160249722-160250695	EUR	0.974	-13958	downstream	2	rs10022399, rs185286,
4:160249722-160250695	SAS	0.974	-13958	downstream	2	rs10022399, rs185286,
4:160250720-160251449	AFR	0.73	-12960	downstream	2	rs58477353, rs5573441,
4:160251451-160258935	all_pop	7.485	-12229	downstream	7	rs56024370, rs62339286, rs11100217, rs1852868, rs70962671, rs6849194, rs684917,
4:160251451-160261893	AMR	10.443	-12229	downstream	15	rs56024370, rs11100216, rs62339286, rs11100217, rs1852868, rs70962671, rs6849194, rs6849170, rs17304561, rs55670915, rs13127789, rs13134868, rs1830456, rs2348167, rs13876094,
4:160251451-160283563	EUR	32.113	-12229	downstream	43	rs56024370, rs62339286, rs11100217, rs1852868, rs70962671, rs6849194, rs6849170, rs17304561, rs55670915, rs13127789, rs13134868, rs1830456, rs2348167, rs138760940, rs10562531, rs10084914, rs17038048, rs3749465, rs41280511, rs12510638, rs11723634, rs13147632, rs11100218, rs6536412, rs11727094, rs3840264, rs56145594, rs11320537, rs10034898, rs11381317, rs13136261, rs13115272, rs1135004, rs7699385, rs7678504, rs13131141, rs10025560, rs6816166, rs3840263, rs13152272, rs6536413, rs1969578, rs1730541,
4:160251451-160257309	SAS	5.859	-12229	downstream	6	rs56024370, rs62339286, rs11100217, rs548078208, rs1852868, rs7096267,
4:160251453-160251984	AFR	0.532	-12227	downstream	2	rs370631228, rs2840978,
4:160252471-160261725	AFR	9.255	-11209	downstream	27	rs10010980, rs74641551, rs116260015, rs115445543, rs62339286, rs10020558, rs11100217, rs140493093, rs17038044, rs1852868, rs140057570, rs144340048, rs70962671, rs115009305, rs79534344, rs114927349, rs111271935, rs113056206, rs6849194, rs6849170, rs28757609, rs138999530, rs17304561, rs55670915, rs13127789, rs13134868, rs183045,
4:160255158-160261893	EAS	6.736	-8522	downstream	13	rs62339286, rs11100217, rs1852868, rs70962671, rs6849194, rs6849170, rs17304561, rs55670915, rs13127789, rs13134868, rs1830456, rs2348167, rs13876094,
4:160258934-160260209	SAS	1.276	-4746	downstream	6	rs6849194, rs6849170, rs71609037, rs17304561, rs55670915, rs1312778,
4:160259209-160261893	all_pop	2.685	-4471	downstream	8	rs28757609, rs17304561, rs55670915, rs13127789, rs13134868, rs1830456, rs2348167, rs13876094,
4:160261725-160261893	SAS	0.169	-1955	downstream	3	rs1830456, rs2348167, rs13876094,
4:160261891-160261893	AFR	0.003	-1789	downstream	2	rs2348167, rs13876094,
4:160262297-160270232	AFR	7.936	-1383	downstream	19	rs145563090, rs17038045, rs10084914, rs17038048, rs3749465, rs17038049, rs79864624, rs12510638, rs78495162, rs11723634, rs58730870, rs13147632, rs11100218, rs9631759, rs6536412, rs113205356, rs10013961, rs3805139, rs1172709,
4:160263874-160271017	all_pop	7.144	194	upstream	11	rs10084914, rs17038048, rs3749465, rs12510638, rs11723634, rs13147632, rs11100218, rs6536412, rs11727094, rs3840264, rs5614559,
4:160263874-160274180	AMR	10.307	194	upstream	14	rs10084914, rs17038048, rs3749465, rs12510638, rs11723634, rs13147632, rs11100218, rs6536412, rs535256944, rs11727094, rs3840264, rs56145594, rs11320537, rs1003489,
4:160263874-160271017	EAS	7.144	194	upstream	7	rs10084914, rs17038048, rs12510638, rs11100218, rs6536412, rs11727094, rs5614559,
4:160263874-160274180	SAS	10.307	194	upstream	14	rs10084914, rs17038048, rs3749465, rs372133400, rs12510638, rs11723634, rs13147632, rs11100218, rs6536412, rs11727094, rs3840264, rs56145594, rs11320537, rs1003489,
4:160271642-160272454	AFR	0.813	7962	upstream	2	rs115998810, rs20104541,
4:160274180-160285544	EAS	11.365	10500	upstream	15	rs10034898, rs11381317, rs13136261, rs58133852, rs1135004, rs7699385, rs7678504, rs10025560, rs6816166, rs3840263, rs6536413, rs17305415, rs9631749, rs2016061, rs1314300,
4:160274417-160275767	AFR	1.351	10737	upstream	3	rs79509764, rs13136261, rs14960407,
4:160275633-160286060	all_pop	10.428	11953	upstream	21	rs13136261, rs13115272, rs1135004, rs7699385, rs7678504, rs13131141, rs10025560, rs6816166, rs3749464, rs3840263, rs34604884, rs13152272, rs571091561, rs6536413, rs1969578, rs17305415, rs9631749, rs17038086, rs2016061, rs13143005, rs768570,
4:160275633-160285544	AMR	9.912	11953	upstream	15	rs13136261, rs13115272, rs1135004, rs7699385, rs7678504, rs13131141, rs10025560, rs6816166, rs3840263, rs13152272, rs6536413, rs1969578, rs9631749, rs2016061, rs1314300,
4:160275633-160283563	SAS	7.931	11953	upstream	13	rs13136261, rs13115272, rs1135004, rs7699385, rs7678504, rs13131141, rs10025560, rs6816166, rs3840263, rs13152272, rs6536413, rs1969578, rs1730541,
4:160277276-160282749	AFR	5.474	13596	upstream	16	rs1135004, rs7699385, rs140344906, rs7678504, rs13131141, rs10025560, rs6816166, rs3749464, rs3840263, rs79848010, rs34604884, rs571091561, rs80210465, rs78894209, rs6536413, rs7944247,
4:160283091-160283692	AFR	0.602	19411	upstream	3	rs1969578, rs139284559, rs1233123,
4:160284153-160286060	AFR	1.908	20473	upstream	7	rs9631749, rs17038081, rs17038083, rs17038086, rs2016061, rs13143005, rs768570,
4:160284153-160285544	EUR	1.392	20473	upstream	3	rs9631749, rs2016061, rs1314300,
4:160284153-160285544	SAS	1.392	20473	upstream	3	rs9631749, rs2016061, rs1314300,
4:160286446-160288440	AFR	1.995	22766	upstream	17	rs7691045, rs114201785, rs9991799, rs370258878, rs58592783, rs148560888, rs28663697, rs28545001, rs575694675, rs28374866, rs113835548, rs28688434, rs57640283, rs11298198, rs6857628, rs6857976, rs1051770,
4:160286446-160289176	all_pop	2.731	22766	upstream	11	rs7691045, rs9991799, rs370258878, rs58592783, rs28374866, rs28688434, rs11298198, rs6857628, rs6857976, rs10517702, rs7270121,
4:160286446-160286997	AMR	0.552	22766	upstream	4	rs7691045, rs9991799, rs370258878, rs5859278,
4:160286446-160292612	EAS	6.167	22766	upstream	13	rs7691045, rs9991799, rs370258878, rs58592783, rs117080856, rs11298198, rs6857628, rs6857976, rs10517702, rs11298109, rs13128547, rs13102815, rs1251026,
4:160286446-160286997	EUR	0.552	22766	upstream	4	rs7691045, rs9991799, rs370258878, rs5859278,
4:160286446-160289176	SAS	2.731	22766	upstream	9	rs7691045, rs9991799, rs370258878, rs58592783, rs11298198, rs6857628, rs6857976, rs10517702, rs7270121,
4:160288005-160292612	AMR	4.608	24325	upstream	9	rs11298198, rs6857628, rs6857976, rs10517702, rs72701215, rs11298109, rs13128547, rs13102815, rs1251026,
4:160288005-160292612	EUR	4.608	24325	upstream	10	rs11298198, rs17305555, rs6857628, rs6857976, rs10517702, rs72701215, rs11298109, rs13128547, rs13102815, rs1251026,
4:160290047-160293799	AFR	3.753	26367	upstream	13	rs9685433, rs74781004, rs13128547, rs149779991, rs141708682, rs13102815, rs111670546, rs12510266, rs57696778, rs150689886, rs1881754, rs11100219, rs1110022,
4:160290806-160292612	all_pop	1.807	27126	upstream	3	rs13128547, rs13102815, rs1251026,
4:160290806-160292612	SAS	1.807	27126	upstream	3	rs13128547, rs13102815, rs1251026,
4:160293543-160294374	all_pop	0.832	29863	upstream	4	rs1881754, rs11100219, rs11100220, rs11239773,
4:160294374-160294375	AFR	0.002	30694	upstream	2	rs112397739, rs11238691,
4:160294475-160294481	AFR	0.007	30795	upstream	2	rs57147050, rs14601681,
4:160294833-160297082	AFR	2.25	31153	upstream	7	rs35915272, rs61414284, rs141033683, rs3929625, rs74528494, rs6826922, rs14008311,
4:160294833-160296004	all_pop	1.172	31153	upstream	4	rs35915272, rs61414284, rs3929625, rs682692,
4:160294833-160309968	AMR	15.136	31153	upstream	25	rs35915272, rs61414284, rs3929625, rs6826922, rs35864474, rs386402024, rs12505807, rs12505843, rs11939143, rs13110592, rs10006236, rs10016829, rs6838473, rs6844376, rs181286908, rs10002330, rs12499113, rs7653996, rs145934311, rs13143735, rs3857016, rs3857017, rs11282807, rs7680415, rs768063,
4:160294833-160309968	EAS	15.136	31153	upstream	24	rs35915272, rs3929625, rs6826922, rs35864474, rs386402024, rs78307328, rs12505807, rs12505843, rs117380824, rs10006236, rs10016829, rs6838473, rs6844376, rs10002330, rs12499113, rs2699012, rs7653996, rs145934311, rs13143735, rs3857016, rs3857017, rs11282807, rs7680415, rs768063,
4:160294833-160297086	EUR	2.254	31153	upstream	4	rs35915272, rs3929625, rs6826922, rs3586447,
4:160295517-160310851	SAS	15.335	31837	upstream	24	rs3929625, rs6826922, rs35864474, rs386402024, rs12505807, rs12505843, rs35602573, rs13110592, rs10006236, rs10016829, rs6838473, rs6844376, rs10002330, rs12499113, rs2699012, rs7653996, rs145934311, rs13143735, rs3857016, rs3857017, rs11282807, rs7680415, rs7680635, rs1000993,
4:160297086-160297414	AFR	0.329	33406	upstream	2	rs35864474, rs14277473,
4:160297782-160297871	AFR	0.09	34102	upstream	2	rs111301395, rs11307229,
4:160298968-160299086	all_pop	0.119	35288	upstream	2	rs12505807, rs1250584,
4:160299086-160303393	AFR	4.308	35406	upstream	18	rs12505843, rs116480722, rs11939143, rs28889884, rs141909825, rs114953997, rs13110592, rs10006236, rs10016829, rs57299850, rs72967780, rs57946912, rs116343924, rs536709695, rs6838473, rs199942655, rs76736807, rs684437,
4:160299086-160310851	EUR	11.766	35406	upstream	21	rs12505843, rs72701219, rs13110592, rs10006236, rs10016829, rs6838473, rs6844376, rs10002330, rs12499113, rs2699012, rs7653996, rs77084032, rs145934311, rs13143735, rs62339328, rs3857016, rs3857017, rs11282807, rs7680415, rs7680635, rs1000993,
4:160299586-160310851	all_pop	11.266	35906	upstream	21	rs11939143, rs28889884, rs13110592, rs10006236, rs10016829, rs6838473, rs6844376, rs10002330, rs12499113, rs2699012, rs7653996, rs11100221, rs145934311, rs72967784, rs13143735, rs3857016, rs3857017, rs11282807, rs7680415, rs7680635, rs1000993,
4:160304978-160309846	AFR	4.869	41298	upstream	12	rs79826267, rs12499113, rs7653996, rs11100221, rs145934311, rs72967784, rs13143735, rs3857016, rs3857017, rs147487503, rs11282807, rs768041,
4:160310851-160310910	AMR	0.06	47171	upstream	2	rs10009938, rs1210839,
4:160310910-160310924	EAS	0.015	47230	upstream	2	rs12108396, rs7296779,
4:160310959-160314077	AMR	3.119	47279	upstream	11	rs10012081, rs13151398, rs10452221, rs112500859, rs7440617, rs2707657, rs7665063, rs11732785, rs7695927, rs7671909, rs269900,
4:160311126-160312527	all_pop	1.402	47446	upstream	5	rs13151398, rs10452221, rs112500859, rs7440617, rs270765,
4:160311126-160314077	EUR	2.952	47446	upstream	11	rs13151398, rs10452221, rs112500859, rs145338432, rs7440617, rs2707657, rs7665063, rs11732785, rs7695927, rs7671909, rs269900,
4:160311436-160312527	AFR	1.092	47756	upstream	7	rs10452221, rs187459640, rs112500859, rs115284525, rs7440617, rs147412567, rs270765,
4:160311436-160322728	SAS	11.293	47756	upstream	30	rs10452221, rs112500859, rs7440617, rs2707657, rs7665063, rs11732785, rs7695927, rs7671909, rs2699005, rs111295346, rs7669477, rs549715907, rs7692457, rs7697362, rs11730417, rs72312207, rs1881753, rs2005582, rs1852869, rs567146086, rs11732754, rs1852870, rs35658568, rs6536415, rs6536416, rs6536417, rs11341844, rs2463988, rs72967796, rs11351314,
4:160311666-160323894	EAS	12.229	47986	upstream	28	rs112500859, rs7440617, rs2707657, rs7665063, rs11732785, rs7695927, rs7671909, rs2699005, rs111295346, rs7669477, rs549715907, rs7692457, rs7697362, rs72312207, rs1881753, rs2005582, rs1852869, rs11732754, rs1852870, rs35658568, rs6536415, rs6536416, rs6536417, rs11341844, rs2463988, rs72967796, rs113513146, rs13839833,
4:160312788-160312930	AFR	0.143	49108	upstream	2	rs7665063, rs1173278,
4:160312788-160312930	all_pop	0.143	49108	upstream	2	rs7665063, rs1173278,
4:160313516-160314216	AFR	0.701	49836	upstream	7	rs111858823, rs7695927, rs7671909, rs189232127, rs113031552, rs2699005, rs7803800,
4:160313634-160314545	all_pop	0.912	49954	upstream	5	rs7695927, rs7671909, rs189232127, rs2699005, rs56395907,

No Alu found near the repeat

Conservation score was not calculated